Background Pancreatic ductal adenocarcinoma (PDAC) is largely refractory to immune checkpoint blockade, owing to its ...

Plants do not wait hours to respond to intense sunlight—they react within minutes. Researchers at Bielefeld University and ...

A cutting-edge mini-review published in the inaugural issue of Targetome elaborates on the value of proteome-wide ...

Tiny silica nanoparticles engineered to seek out prostate cancer caused tumor cells to self-destruct and supercharged the ...

Life Biosciences has received FDA clearance to begin a first-in-human Phase 1 clinical trial of ER-100, a gene therapy designed to reverse cellular aging in the human eye. The trial, registered as ...

A team linked to Harvard Medical School has dosed the first patient in a clinical trial designed to reverse cellular aging in the human eye. The study, called ER-100, uses a gene therapy vector to ...

Scientists say they have built a cell from scratch for the first time that feeds, grows and replicates like a natural cell, a breakthrough in synthetic biology.

Direct neuronal reprogramming enables the generation of neurons from somatic cells without passing through a pluripotent state, yet the post-transcriptional mechanisms that refine neuronal identity ...

A newly discovered molecule, OLE, restored the brain's immune cells to a more protective state in Alzheimer's disease models. The treatment reduced the accumul ...

Dendritic cells (DCs) are indispensable orchestrators of antitumor immunity, yet in solid tumors, they frequently undergo profound dysfunction, enabling immune evasion and cancer progression. Recent ...

Promising mouse studies and billions of dollars in funding are stoking excitement. But we’ve been here before. Earlier this week, Life Biosciences, a biotech company focused on reversing age-related ...