The unveiling of the DNA sequences of human chromosomes represents a new chapter in the unfolding story of genomics, but one with roots in the half-century-old field of cytogenetics. Chromosome-level ...

Conservation of genomic sequences between species indicates regions of functional importance, containing protein-coding gene, non-coding genes or regulatory elements. In the December 5 Nature, ...

Three copies of chromosome 21 causes Down syndrome (DS), and roughly half of children born each year in the United States with DS-approximately 2,600-also have congenital heart defects (CHDs). What is ...

How does the CRISPR Down Syndrome breakthrough work to remove the extra chromosome 21? We are closer than ever to a world where a genetic condition affecting one in every 700 babies could be addressed ...

Jenny Graves is a Friend of The Conversation. Neanderthals, the closest cousins of modern humans, lived in parts of Europe and Asia until their extinction some 30,000 years ago. Genetic studies are ...