A previously unknown type of DNA damage in the mitochondria, the tiny power plants inside our cells, could shed light on how our bodies sense and respond to stress. The findings of the UC ...
The tiny little powerhouses of our cells: mitochondria, are unique among organelles because they carry their own tiny little genomes. This genetic material is separate from the rest of our genomic DNA ...
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A research team from the University of California (UC), Irvine, has revealed a previously unknown mechanism that triggers an inflammatory immune response in cells when their DNA is damaged. The ...
Despite the significance of immune checkpoint inhibitors (ICIs) in solid tumor treatment, identifying ICI-sensitive populations remains a challenge. Mutations in DNA damage response (DDR) pathway ...
DNA's iconic double helix does more than "just" store genetic information. Under certain conditions, it can temporarily fold ...
The study assesses pesticide exposure and DNA damage in 45 Latinx children ages 10 to 12 from rural, farmworker families (30) and urban, non-farmworker families (15). Participants were selected from a ...