RNA is key to the dark matter of the genome − scientists are sequencing it to illuminate human health and disease

Although there are striking differences between the cells that make up your eyes, kidneys, brain and toes, the DNA blueprint for these cells is essentially the same. Where do those differences come ...

DeepChopper model improves RNA sequencing research by mitigating chimera artifacts

Scientists in the laboratory of Rendong Yang, Ph.D., associate professor of Urology, have developed a new large language model that can interpret transcriptomic data in cancer cell lines more ...
Kaleido Scope

UAB researchers uncover protein SRSF1’s uncommon ability to bind and unfold RNA G-quadruplexes

RNA transcription is the genomic process in which a cell produces a duplicate of a gene’s DNA sequence. Present in both DNA and RNA sequences, a G-quadruplex (GQ) is a structure of four guanine bases ...
Wired

Cells From Different Species Can Exchange ‘Text Messages’ Using RNA

The original version of this story appeared in Quanta Magazine. For a molecule of RNA, the world is a dangerous place. Unlike DNA, which can persist for millions of years in its remarkably stable, ...
Labroots

Odd RNA Caps Reveal a New Kind of Gene Transcription

Scientists have found a new process that happens when an active gene is transcribed from DNA into messenger RNA.. | Cell And ...