AP180 is a protein involved in endocytosis and in signal transmission between nerve cells. This protein, which largely lacks a three-dimensional structure, has never been fully studied. To allow ...

Study demonstrates a new way to study flu-host interactions in their native context and with structural insight.

Inside every human cell, proteins are constantly being tagged with small chemical modifications after they're produced. Known as post-translational modifications, or PTMs, these can change how a ...

Scientists from Cleveland Clinic and Cornell University have designed a publicly-available software and web database to break down barriers to identifying key protein-protein interactions to treat ...

Scientists have used deep learning to design new proteins that bind to complexes involving other small molecules like hormones or drugs, opening up a world of possibilities in the computational design ...

Researchers capture first-of-its-kind video of dynein–Lis1 protein interaction, supporting future drug development for neurological disorders. Our cells rely on microscopic highways and specialized ...

Protein–phenolic interactions encompass a diverse array of molecular associations between food-derived proteins and plant secondary metabolites known as polyphenols. These interactions may proceed via ...

Protein-Protein Interactions (PPIs) are critical for biological systems to function properly. Strong interactions maintain structural integrity and function, whereas weaker interactions enable ...

OverviewProteins are not static molecular objects but dynamic conformational ensembles whose structures, motions, disorder, ...

Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...

In the early 1980s, David Gilmour, now an emeritus biochemistry and molecular biology professor at Pennsylvania State University, joined the laboratory of geneticist and biochemist John Lis as a ...