Every time a cell divides, it must copy its DNA with extraordinary precision. But this process is constantly challenged by DNA damage. Among the most dangerous lesions are DNA interstrand crosslinks ...
To better understand BKPyV replication and ways to prevent it, researchers in the UAB Department of Microbiology have published a single-cell analysis of BKPyV infection in primary kidney cells. Their ...
Damage to DNA in cancer cells can lead to pieces breaking off chromosomes and floating away, like icebergs cracking off from ...
R-loops are structures that form when a strand of RNA (red) forms a stable structure with double-stranded DNA, causing one strand of the DNA to form a loop. R-loops are associated with gene ...
Researchers at The University of Texas MD Anderson Cancer Center have performed a comprehensive evaluation of five artificial intelligence (AI) models trained on genomic sequences, known as DNA ...
Long-Term Survival and Biomarker Analysis Evaluating Neoadjuvant Plus Adjuvant Relatlimab (anti-LAG3) and Nivolumab (anti-PD1) in Patients With Resectable Melanoma Our study included a broad cohort of ...
Most people are familiar with the DNA double-helix. Its twisted ladder shape forms because the long pieces of DNA that make up our genome are exactly complementary—every adenine paired to a thymine, ...
A simulated cell in the early stages of division. Left half shows cytoplasm (blue cubes), mRNA degradation machinery molecules (pink), and sugar transporters (brown). Right half adds the membrane ...